GENEVA (AFP) - The World Health Organisation warned Wednesday that drug resistance fuelled partly by misuse of antibiotics is killing hundreds of thousands of people a year and that urgent action was needed on the issue. Were really seeing an accelerated evolution in the spread of this problem and the bottom line is that the problem is outpacing the solutions, said Keiji Fukuda, WHO assistant director general. Health experts noted that few countries across the world had plans to deal with the problem, which was increasing amid increased consumption of antibiotics. In the vast majority of the countries there are no plans, no budgets, there are no accountability lines for this extremely serious problem, said Mario Raviglione, who heads the WHOs campaign against tuberculosis. Surveillance systems are weak, they are absent in many places, he noted, adding that the quality of antibiotics is questionable in some of these countries. Suboptimal doses are actually those that steer the mechanism to develop drug resistance. The use of antibiotics is often inappropriate, we call it irrational. It facilitates the creation of drug resistance. In addition, the use of antibiotics in livestock production to promote growth and prevent diseases as well as to treat sick animals also contributes to increased drug resistance. Any drug-resistant microbes developed in livestock can be transferred to humans through the food chain. As microbes will always seek to become resistant to drugs, the problem is never going to go away, noted Fukuda. The more important issue is how long it would be to step up to the plate and get action underway, he said. The UN health agency is highlighting the problem on the occasion of this years World Health Day.