Muttahida Qaumi Movement (MQM) MPA Manzar Imam was killed in firing incident at Orangi area of the city here on Thursday.
Three of his security guards also killed in the incident.
According to police and rescue sources, he was severely wounded when unidentified gunmen opened fire on his car. He succumbed to his injuries being taken to a hospital.
After the incident, tension prevailed in several areas of the city while police started investigations into the incident.